vai al contenuto della pagina vai al menu di navigazione
 

Research

The Health Sciences & Technologies (HST) CIRI is engaged in furthering the three-year programme of activities defined by the “Regional Technopole” project, and summarized in three macro-areas: diagnosis, therapy, and health care.

Ongoing research at the HST-CIRI includes projects funded by public agencies and foundations (Telethon, AIRC), and projects commissioned by enterprises, in some cases with public co-financing.

Research fields

Diagnosis
Development of technologies for early diagnosis, DNA analysis and drug screening.
Therapy
Identification of novel therapeutic targets, applications in regenerative medicine.
Health care
Research for new technologies to improve the autonomy and quality of life of the elderly and the sick.

Technologies

Biosensors
Modeling, design, realization and characterization of biosensors.
High content analysis
Instruments, reagents and equipment are available for the screening of bioactive molecules and chemical libraries to provide quantitative information about the effect of molecules on cell phenotype via high-throughput cell-based high content analysis.
DNA engineering
We use genetic technologies for cell manipulation and for the creation of dedicated cell lines, including human mutation cell models and stem cell models.
Microscopy and image analysis
Our laboratories are equipped with systems of conventional microscopy, fluorescence, confocal laser-scanning for time lapse observation, and software for image analysis in 2D, 3D and 4D for the quantitative analysis of images. We therefore offer a service of morphometric and micro-densitometric measurements for the study of toxicity and efficacy of bioactive molecules, drugs, new therapies.
Stem cells
We research the application of stem cells in screening and regenerative medicine.
3D Fluoroscopy
We have developed a software library for 3D fluoroscopy to analyse the movement of joints and prostheses. We can measure human joint movement with a high accuracy using advanced analytical techniques based on 2D and 3D X-ray images. This analysis can be used to perform a clinical evaluation of the patient’s health status.
Biofeedback rehabilitation technologies
We design and develop biofeedback oriented software to improve the rehabilitation process. For example, we have developed an application to analyse the kinetics of the sodium ion in body compartments during dialysis therapy.
Numerical simulation
Digital models are very useful to describe in detail biological phenomena in order to study or clinically check them in various areas of pathophysiology.
Electrospinning
Fabrication of nanofibrous membranes and scaffolds through electrospinning technology is aimed at providing innovative polymeric materials with tailored functionalities for biomedical applications, such as tissue engineering.
e-health
Electronic devices can be used for biomedical applications to facilitate diagnosis and patient care. We design and develop custom systems using smart devices to perform data capture using wireless sensor networks, and data processing. The aim of these systems is to provide a smart environment able to interact with the users inside it.
Mechanical characterization of tissues and bio-compatible materials
We have the expertise and technologies necessary to study the mechanical response of tissues and the production of materials and biocompatible prosthetic grafts.