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Technologies

The HST CIRI provides advanced measurement, observation and analysis technologies and relative internal support to businesses. We also offer the technical expertise that follows from our diverse activities.

Stem cells
We have skills in the isolation, expansion, and differentiation of stem cells from different animal and human tissues, ranging from embryonic animals used for the development of diagnostic tools and biosensors, to autologous human mesenchymal stem cell used for therapy and regenerative medicine.
Biosensors
We have considerable expertise in the modelling, design, building and characterization of biosensors using techniques of rapid prototyping, microfluidics, electrochemistry, electronics, optics and in vitro cell manipulation.
High content analysis
Instruments, reagents and equipment are available for the screening of bioactive molecules and chemical libraries to provide quantitative information about the effect of molecules on cell phenotype via high-throughput cell-based high content analysis.
Microscopy and image analysis
Our laboratories are equipped with systems of conventional microscopy, fluorescence, confocal laser-scanning for time lapse observation, and software for image analysis in 2D, 3D and 4D for the quantitative analysis of images. We therefore offer a service of morphometric and micro-densitometric measurements for the study of toxicity and efficacy of bioactive molecules, drugs, new therapies.
3D Fluoroscopy
We have developed the software MultiTrack™ for 3D fluoroscopy to analyse the movement of joints and prostheses. We can measure human joint kinematics with high accuracy using advanced analytical techniques based on 2D and 3D images. This analysis can be used to perform clinical evaluations of the patient’s health status or to quantify the outcome of surgery and rehabilitation.
Biofeedback rehabilitation technologies
We design and develop biofeedback oriented software to improve the rehabilitation process. For example, we have developed an application to analyse the kinetics of the sodium ion in body compartments during dialysis therapy.
Electrospinning
Fabrication of nanofibrous membranes and scaffolds through electrospinning technology is aimed at providing innovative polymeric materials with tailored functionalities for biomedical applications, such as tissue engineering.
e-health
Electronic devices can be used for biomedical applications to facilitate diagnosis and patient care. We design and develop custom systems using smart devices to perform data capture using wireless sensor networks, and data processing. The aim of these systems is to provide a smart environment able to interact with the users inside it.
Mechanical characterization of tissues and bio-compatible materials
We have the expertise and technologies necessary to study the mechanical response of tissues and the production of materials and biocompatible prosthetic grafts.
DNA engineering
We use genetic technologies for cell manipulation and for the creation of dedicated cell lines, including human mutation cell models and stem cell models.
Numerical simulation
Digital models are very useful to describe in detail biological phenomena in order to study or clinically check them in various areas of pathophysiology.